Chairman's Annual Report 2016

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Medication Slows Devastating Lung Disease

Medication Slows Devastating Lung Disease

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Genetic Link to Sudden Cardiac Death Revealed

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Joshua M. Hare, M.D.

Study Shows Stem Cell Therapy Dosing Matters in Ischemic Cardiomyopathy

The Phase II TRIDENT study, led by Joshua M. Hare, M.D., and colleagues at the University of Miami Miller School of Medicine, found that a dose of 100 million allogeneic human mesenchymal stem cells, versus 20 million, was more effective in decreasing scar tissue and restoring left ventricular ejection fraction in study of 30 people with ischemic cardiomyopathy.

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Nanette H. Bishopric, M.D.

Researchers Explore First Treatment for Common Form of Heart Failure

The heart adapts to many types of chronic stress by undergoing hypertrophy, a thickening of the heart muscle. There is currently no treatment for hypertrophy, but researchers at the University of Miami Miller School of Medicine are conducting studies that may lead to the first. They have shown that hypertrophy develops when stress causes two key proteins to interact in the cell nucleus, altering the expression of many genes.

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Gilberto de Lima Lopes, Jr., M.D., M.B.A.

Sylvester Researcher Identifies Tumor Biomarker to Guide Lung Cancer Immunotherapy

A predictive tumor biomarker can help clinicians identify lung cancer patients who are most likely to benefit from immunotherapy, according to Gilberto de Lima Lopes, Jr., M.D., M.B.A., a researcher at the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

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